Thermo Fisher Scientific BCL11A Polyclonal Antibody
Mouse BCL11A 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. 합성 펩타이드 면역원으로 제작되었으며, Affinity chromatography로 정제되었습니다. PBS와 sucrose buffer에 보관되며, 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal region of mouse BCL11A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2690140 |
Product Specific Information
This target displays homology in the following species:
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 92%; Rat: 92%
Target Information
This gene encodes a C2H2 type zinc-finger protein similar to the mouse Bcl11a/Evi9 protein.
The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia and may function as a leukemia disease gene through its interaction with BCL6.
During hematopoietic cell differentiation, this gene is down-regulated and may be involved in lymphoma pathogenesis since translocations associated with B-cell malignancies deregulate its expression.
Multiple transcript variants encoding several different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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