Thermo Fisher Scientific DLK1 Polyclonal Antibody
DLK1 단백질을 인식하는 Rabbit Polyclonal 항체. Western blot과 Immunocytochemistry에 사용 가능. HepG2 세포 용해물을 양성 대조로 추천. DLK1 관련 세포 분화 및 종양 억제 연구에 적합. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 25 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | An 18 amino acid synthetic peptide near the carboxy terminus of human DLK1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long term storage, store at -20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551785 |
Product Specific Information
- A suggested positive control is HepG2 cell lysate.
- PA5-34433 can be used with blocking peptide PEP-1475.
Target Information
The Delta-like 1 homolog (DLK1) is a transmembrane protein containing six epidermal growth factor repeats. It is involved in the differentiation of several cell types, including adipocytes, and is also thought to be a tumor suppressor.
The DLK1 gene is one of several imprinted genes located in a region on chromosome 14q32; certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14).
DLK1 is expressed from the paternal allele; a polymorphism within this gene has been associated with child and adolescent obesity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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