Thermo Fisher Scientific LCAT Polyclonal Antibody
LCAT 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot, IHC, ICC, ELISA 등 다양한 응용에 적합. Human, Mouse, Rat 반응성. Protein A 정제, 1 mg/mL 농도, -20°C 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human LCAT (amino acids 151–250) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Lecithin: cholesterol acyltransferase (LCAT) is a plasma enzyme responsible for forming most HDL cholesteryl esters in human plasma. In species with cholesteryl ester transfer protein (CETP), it also contributes to VLDL and LDL cholesteryl ester formation.
Through cholesterol esterification, LCAT facilitates reverse cholesterol transport by moving cholesterol from peripheral tissues to the liver for excretion.
LCAT deficiency leads to low plasma HDL, while overexpression increases plasma HDL levels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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