Thermo Fisher Scientific QPRT Polyclonal Antibody, MaxPab
QPRT 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간 시료에 반응하며 Western blot에 적합. 친화 크로마토그래피로 정제된 액상 형태로 제공되며, 방부제 무첨가. 연구용으로만 사용 가능.
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Thermo Fisher Scientific QPRT Polyclonal Antibody, MaxPab
Applications
- Western Blot (WB): Tested dilution 1–5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | QPRT (NP_055113.2, 1–297 a.a.) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MDAEGLALLL PPVTLAALVD SWLREDCPGL NYAALVSGAG PSQAALWAKS PGVLAGQPFF DAIFTQLNCQ VSWFLPEGSK LVPVARVAEV RGPAHCLLLG ERVALNTLAR CSGIASAAAA AVEAARGAGW TGHVAGTRKT TPGFRLVEKY GLLVGGAASH RYDLGGLVMV KDNHVVAAGG VEKAVRAARQ AADFALKVEV ECSSLQEAVQ AAEAGADLVL LDNFKPEELH PTATVLKAQF PSVAVEASGG ITLDNLPQFC GPHIDVISMG MLTQAAPALD FSLKLFAKEV APVPKIH
Target Information
QPRT gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan–nicotinamide adenine dinucleotide pathway. Quinolinate acts as a potent endogenous excitotoxin to neurons. Elevated quinolinate levels in the brain have been linked to neurodegenerative disorders such as epilepsy, Alzheimer’s disease, and Huntington’s disease.
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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