Thermo Fisher Scientific EMR4P Monoclonal Antibody (1G10)

Applications and Tested Dilution

Product Specifications

Product Specific Information

Sequence of this protein is as follows:
GSEAKNSGAS CPPCPKYASC HNSTHCTCED GFRARSGRTY FHDSSEKCED INECETGLAK CKYKAYCRNK VGG

Target Information

FIRE is a 689 amino acid protein that maps to the human gene EMR4.
FIRE (also known as EGF-like module-containing mucin-like hormone receptor-like 4) belongs to the G protein-coupled receptor 2 family, LN-TM7 subfamily.
The EGF-TM7 family includes proteins with EGF-like extracellular domains coupled to a classical seven-transmembrane (TM7) cassette.
FIRE mediates cellular interactions between myeloid cells and beta cells and is a membrane-bound, multi-pass protein cleaved into two subunits: an extracellular alpha subunit and a seven-transmembrane subunit.
It contains one GPS (G protein-coupled receptor proteolytic cleavage site) domain and two EGF-like domains, the second of which is involved in ligand interaction.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.