Thermo Fisher Scientific EMR4P Monoclonal Antibody (1G10)
EMR4P 단백질을 인식하는 Mouse IgG2a 단클론 항체로 Western blot, ICC/IF, ELISA에 사용 가능. 인간 시료 반응성. PBS 버퍼에 용해된 액상 형태이며, 친화 크로마토그래피로 정제됨. 연구용으로만 사용.
- 카탈로그번호
- H00326342-M02
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| ELISA | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1G10 |
| Immunogen | EMR4P (XP_377506, 21 a.a. approximately 93 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
GSEAKNSGAS CPPCPKYASC HNSTHCTCED GFRARSGRTY FHDSSEKCED INECETGLAK CKYKAYCRNK VGG
Target Information
FIRE is a 689 amino acid protein that maps to the human gene EMR4.
FIRE (also known as EGF-like module-containing mucin-like hormone receptor-like 4) belongs to the G protein-coupled receptor 2 family, LN-TM7 subfamily.
The EGF-TM7 family includes proteins with EGF-like extracellular domains coupled to a classical seven-transmembrane (TM7) cassette.
FIRE mediates cellular interactions between myeloid cells and beta cells and is a membrane-bound, multi-pass protein cleaved into two subunits: an extracellular alpha subunit and a seven-transmembrane subunit.
It contains one GPS (G protein-coupled receptor proteolytic cleavage site) domain and two EGF-like domains, the second of which is involved in ligand interaction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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