
Thermo Fisher Scientific BCOR Polyclonal Antibody
BCOR 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(P) 실험에 적합합니다. Human과 Mouse 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS/glycerol 저장용액에 1 mg/mL 농도로 제공됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from internal region of human BCOR (aa 1250–1271) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2635357 |
Product Specific Information
This antibody detects endogenous levels of total BCOR protein.
Target Information
BCOR (BCL6 Corepressor) is a transcriptional corepressor that may inhibit gene expression when recruited to promoter regions by sequence-specific DNA-binding proteins such as BCL6 and MLLT3. This repression may involve histone deacetylase activities associated with BCOR. It is involved in repression of TFAP2A and negatively regulates osteo-dentiogenic capacity in adult stem cells by inhibiting methylation on histone H3 Lys-4 (H3K4me3) and Lys-36 (H3K36me2).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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