Thermo Fisher Scientific TRPA1 Polyclonal Antibody, Biotin
TRPA1 단백질을 표적하는 Biotin 결합 폴리클로날 항체로, WB, IHC, ICC, Flow, ELISA 등 다양한 응용에 사용 가능. Rabbit IgG 기반으로 높은 특이성과 민감도 제공. 인간, 생쥐, 랫드, 기니피그, 제브라피쉬 반응성. 연구용으로만 사용.
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Thermo Fisher Scientific TRPA1 Polyclonal Antibody, Biotin
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:250 |
| Immunohistochemistry (Frozen) (IHC (F)) | 0.5–1.0 µg/mL |
| Immunocytochemistry (ICC/IF) | Assay-Dependent |
| Flow Cytometry (Flow) | Assay-Dependent |
| ELISA | Assay-Dependent |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Guinea pig, Human, Mouse, Rat, Zebrafish |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide from N-terminus (residues 1–100) of human TRPA1 protein |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.96 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11153917 |
Product Specific Information
- Target sequence has 69% sequence homology with rat.
- Suggested positive control: human brain membrane fraction.
Target Information
TRPA1 is a TRP-related ion channel that responds to cold temperatures and pungent compounds, playing a role in nociceptor and hair cell transduction. It is associated with transformation in lung epithelia and mainly expressed in sensory neurons. Blocking TRPA1 may provide a therapeutic approach for cold hyperalgesia due to inflammation or nerve injury. TRPA1 is also expressed outside the CNS and is dysregulated during oncogenic transformation. Structurally, it is related to ankyrin and transmembrane proteins, potentially involved in signal transduction and growth control.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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