Thermo Fisher Scientific MMP11 Recombinant Rabbit Monoclonal Antibody (ARC0523)
MMP11 단백질을 인식하는 Thermo Fisher의 재조합 토끼 단일클론 항체입니다. Western blot과 ELISA에 적합하며, 인간, 마우스, 랫트 시료에 반응합니다. HEK293 세포에서 발현된 IgG 형 항체로, 고순도 친화 크로마토그래피 정제 제품입니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:4,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC0523 |
| Immunogen | Synthetic peptide corresponding to amino acids 389–488 of human MMP11 (P24347) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.43 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS (pH 7.3), with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20 °C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2848972 |
Product Specific Information
Immunogen sequence:
AALVWGPEKN KIYFFRGRDY WRFHPSTRRV DSPVPRRATD WRGVPSEIDA AFQDADGYAY FLRGRLYWKF DPVKVKALEG FPRLVGPDFF GCAEPANTFL
Target Information
Stromelysin, a member of the matrix metalloproteinase family, demonstrates wide substrate specificity with the ability to degrade proteoglycan, fibronectin, laminin, casein, and the nonhelical region of collagen. The stromelysin-3 (MMP-11) gene was originally identified on the basis that it is expressed specifically in stromal cells surrounding invasive breast carcinomas. MMP-11 is localized by in situ hybridization to the long arm of chromosome 22. The MMP-11 expression is found more specifically in malignant tumors than in benign ones.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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