Thermo Fisher Scientific Human VLK Synthetic Peptide
인간 VLK 단백질의 중앙부 15개 아미노산 서열을 기반으로 한 합성 펩타이드입니다. 항체 PA5-20875의 블로킹 펩타이드로 사용 가능하며, 골지체 관련 단백질 수출 조절 연구에 적합합니다. 연구용으로만 사용됩니다.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 15 amino acids near the center of human VLK.
PEP-0989 can be used as a blocking peptide with polyclonal antibody PA5-20875.
Target Information
VLK was identified as a novel protein kinase induced after differentiation of cultured embryonic stem cells into mesendoderm.
It has no homologs in invertebrates but is highly conserved in vertebrates, although not belonging to any known kinase groups.
VLK is initially expressed in E-cadherin-positive anterior visceral endoderm and mesendoderm, later confined to E-cadherin-negative mesenchyme.
Enriched in the Golgi apparatus, it is thought to regulate protein export from the Golgi.
Targeted disruption of VLK in mice leads to lung development defects and neonatal lethality. Mutations in VLK may be associated with atopy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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