Thermo Fisher Scientific Human KCNK18 Synthetic Peptide
인간 TRESK 단백질의 중심부 17개 아미노산 서열 기반 합성 펩타이드. 항체 PA5-20873의 블로킹 펩타이드로 사용 가능. PBS(pH 7.2)와 0.1% BSA 용액에 200 µg/mL 농도로 제공. 연구용으로만 사용 가능.
- 카탈로그번호
- PEP0987
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 17 amino acids near the center of human TRESK.
PEP-0987 can be used as a blocking peptide with polyclonal antibody PA5-20873.
Target Information
TRESK (TWIK-related spinal cord K⁺ channel) is a two-pore domain K⁺ channel that induces outward rectification and functions as a background K⁺ channel abundantly expressed in the spinal cord, thymus, spleen, and leukemic T-lymphocytes.
TRESK is activated by increased cytoplasmic calcium concentration through calcineurin as well as by acetylcholine and histamine. It has been suggested that TRESK is linked to acute and chronic pain by activation of calcineurin.
Other studies indicate that TRESK may play a role in the regulation of T-cell function and could be an excellent target to treat T-cell originated immune dysfunction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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