Thermo Fisher Scientific UCP1 Polyclonal Antibody
Thermo Fisher Scientific의 UCP1 Polyclonal Antibody는 Western blot에 최적화된 염소 유래 다클론 항체입니다. Rat 반응성이 있으며, 합성 펩타이드 면역원으로 제작되었습니다. 0.5 mg/mL 농도의 액상 형태로 제공되며, -20°C에서 보관합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.5–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (EQLKRELSKSRQ) corresponding to the C-terminus amino acids of UCP1 (aa 290–301) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10982087 |
Product Specific Information
- Predicted to react with canine, mouse, and rat based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 1:128,000.
Target Information
Mitochondrial uncoupling proteins (UCPs) are members of the mitochondrial anion carrier protein family. They separate oxidative phosphorylation from ATP synthesis, dissipating energy as heat (mitochondrial proton leak). UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return of protons inward, reducing mitochondrial membrane potential. Tissue-specific expression varies among UCPs, and the precise mechanism of proton transfer remains unclear. UCP1 is expressed exclusively in brown adipose tissue, specialized for heat production.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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