Thermo Fisher Scientific Phospho-ATF4 (Ser219) Polyclonal Antibody
ATF4 단백질의 Ser219 인산화 부위를 인식하는 Rabbit Polyclonal 항체. Western blot에 적합하며 Human과 Mouse 시료에 반응. 1 mg/mL 농도의 액상 형태로 제공되며, -20°C에서 보관. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
- Suggested positive control: COLO cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide sequence around phosphorylation site of Serine 219 (N-D-S(p)-G-T) derived from Human ATF-4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2554090 |
Product Specific Information
A suggested positive control for Western blot is COLO cells.
Target Information
This gene encodes a transcription factor originally identified as a widely expressed mammalian DNA-binding protein that binds a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein is also known as cAMP-response element binding protein 2 (CREB-2).
The protein belongs to a family of DNA-binding proteins including AP-1, CREB, and CREB-like transcription factors. These share a leucine zipper region for protein–protein interactions and a basic DNA-binding domain.
Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromosome at q28 within a large inverted duplication region.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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