Thermo Fisher Scientific INTU Polyclonal Antibody
Rabbit polyclonal antibody against human INTU protein. Validated for IHC (Paraffin) at 1:20–1:50 dilution. Key role in ciliogenesis and embryonic development studies. Supplied unconjugated in PBS with glycerol, stored at 4°C or −20°C.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): Tested dilution 1:20–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human INTU. Recombinant protein control fragment (Product #RP-96718) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at −20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2642749 |
Product Specific Information
Immunogen sequence:
KTQSNTSDLV KLLWGEEVEG IQQSGLNTPH IIMYLTLQLD SETSKEEQEI LYHYPMSEAS QKLKSVRGIF LTLCDMLENV TGTQVTSSSL L
Highest antigen sequence identity to orthologs:
- Mouse: 77%
- Rat: 55%
Target Information
Plays a key role in ciliogenesis and embryonic development. Regulates cilia formation by organizing the apical actin cytoskeleton and positioning basal bodies at the apical cell surface, essential for proper ciliary microtubule orientation. Contributes to cell polarity definition via its role in ciliogenesis, not via convergent extension. Indirectly affects hedgehog signaling. Proposed as a core component of the CPLANE complex involved in recruiting peripheral IFT-A proteins to basal bodies (PubMed:27158779). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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