Thermo Fisher Scientific INTU Polyclonal Antibody
Human INTU 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 등 다양한 연구용에 사용 가능. Antigen affinity chromatography로 정제되어 높은 특이성과 재현성을 제공. PBS buffer에 40% glycerol 포함, 장기 보관 시 -20°C 권장.
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Thermo Fisher Scientific INTU Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human INTU. Recombinant protein control fragment (Product #RP-103774). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2642750 |
Product Specific Information
Immunogen sequence:
NDNGPVSILK HQSNQKTGVI VQQRYKDVNV YVNPKKLTVI KAKEQLKLLE VLVGIIHQTK WSWRRTGKQG DGERLVVHGL LPGGSAMKSG QVLIGDV
Highest antigen sequence identity to the following orthologs:
- Mouse: 84%
- Rat: 82%
Target Information
Plays a key role in ciliogenesis and embryonic development. Regulates cilia formation by organizing the apical actin cytoskeleton and positioning basal bodies at the apical cell surface, essential for proper orientation of elongating ciliary microtubules. Involved in defining cell polarity via its role in ciliogenesis, not via convergent extension. Indirectly affects hedgehog signaling. Proposed to function as a core component of the CPLANE (ciliogenesis and planar polarity effectors) complex, recruiting peripheral IFT-A proteins to basal bodies (PubMed:27158779). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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