Thermo Fisher Scientific IDH2 Monoclonal Antibody (3E8D12)
인간 IDH2 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot, IHC, ICC, Flow cytometry, ELISA 등 다양한 응용에 적합합니다. 고순도 Protein G 정제 항체이며, 1 mg/mL 농도의 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific IDH2 Monoclonal Antibody (3E8D12)
응용 분야 및 희석 배수
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
제품 사양
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3E8D12 |
| Immunogen | Purified recombinant fragment of human IDH2 (AA: 1–143) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3091252 |
Target Information
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one utilizing NAD and the other NADP as electron acceptors.
Five isocitrate dehydrogenases have been reported: three NAD-dependent (mitochondrial matrix-localized) and two NADP-dependent (one mitochondrial, one cytosolic).
Each NADP-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP-dependent isocitrate dehydrogenase found in mitochondria, involved in intermediary metabolism and energy production, and may interact with the pyruvate dehydrogenase complex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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