Thermo Fisher Scientific FBLIM1 Monoclonal Antibody (OTI3G1), TrueMAB
인간 FBLIM1 단백질을 인식하는 단클론 항체로, Western blot에 최적화됨. 동결건조 형태로 제공되며 PBS 버퍼에 8% 트레할로스 포함. 재구성 후 약 1 mg/mL 농도로 사용 가능. 세포 접착 및 세포골격 연구에 적합.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific FBLIM1 Monoclonal Antibody (OTI3G1), TrueMAB
Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3G1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–242 of human FBLIM1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | –20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The FBLIM1 gene encodes a protein with:
- An N-terminal filamin-binding domain
- A central proline-rich domain
- Multiple C-terminal LIM domains
This protein localizes at cell junctions, linking adhesion structures to the actin cytoskeleton. It is involved in actin filament assembly and stabilization, influencing cell adhesion, morphology, and motility.
Additionally, it localizes to the nucleus and may regulate cardiomyocyte differentiation via interaction with the CSX/NKX2-5 transcription factor.
Alternative splicing produces multiple transcript variants encoding distinct isoforms.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.