
Thermo Fisher Scientific Phospho-Histone H3 (Thr11) Polyclonal Antibody
Histone H3 단백질의 Thr11 인산화 부위를 인식하는 Rabbit Polyclonal 항체. Western blot에 적합하며, 인간, 생쥐, 랫드에 반응. 항원 친화 크로마토그래피로 정제, PBS/glycerol buffer에 보관. 연구용 한정 제품.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide sequence around phosphorylation site of threonine 11 (K-S-T(p)-G-G) derived from Human Histone H3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2608325 |
Product Specific Information
This antibody is predicted to react with mouse and rat based on sequence homology.
Target Information
Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3, along with four core histone proteins, binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication, and chromosomal stability. Post-translational modifications of histones, such as methylation, acetylation, and phosphorylation, influence chromatin structure and gene expression. The N-terminal tail of histone H3 can undergo multiple modifications that regulate cellular processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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