Thermo Fisher Scientific Phospho-Histone H3 (Tyr41) Polyclonal Antibody
Histone H3 Tyr41 인산화 부위를 인식하는 Rabbit Polyclonal 항체로, Western blot에 최적화되어 있습니다. 인간, 마우스, 랫트 시료에 반응하며 항원 친화 크로마토그래피로 정제되었습니다. -20°C 보관, 연구용 전용 제품입니다.
- 카탈로그번호
- PA540142
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide sequence around phosphorylation site of tyrosine 41 (H-R-Y(p)-R-P) derived from Human Histone H3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2608328 |
Product Specific Information
This antibody is predicted to react with mouse and rat based on sequence homology.
Target Information
Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3, along with four core histone proteins, binds to DNA forming the nucleosome structure. Histones play a central role in transcription regulation, DNA repair, DNA replication, and chromosomal stability. Post-translational modifications of histones can alter chromatin structure or facilitate transcription factor binding. The N-terminal tail of histone H3 can undergo various modifications such as methylation, acetylation, and phosphorylation, influencing key cellular processes.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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