Thermo Fisher Scientific Glutaminase C (GAC) Polyclonal Antibody
Glutaminase C(GAC) 단백질을 특이적으로 인식하는 Rabbit Polyclonal 항체. Western blot, IHC, ICC/IF, IP 등 다양한 응용에 적합. 인간 및 생쥐 시료에 반응하며, 항원 친화 크로마토그래피로 정제됨. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:10,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
| Immunoprecipitation (IP) | 1:100–1:500 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the C-terminus region of human Glutaminase C |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2609956 |
Product Specific Information
- This antibody specifically recognizes GAC but not the KGA isoform.
- Predicted reactivity: Bovine (100%).
- Recommended positive controls: MDA-MB-231 and cholangiocarcinoma tissue.
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Phosphate-activated glutaminase (EC 3.5.1.2) is the major enzyme that converts glutamine to glutamate. It plays a key role in neurotransmitter-related processes. Studies have shown high heritability of platelet glutaminase activity, suggesting genetic influence on enzyme expression and potential links to behavioral conditions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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