Thermo Fisher Scientific D4 Dopamine Receptor Polyclonal Antibody
D4 도파민 수용체를 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ELISA에 적합합니다. Mouse와 Rat 조직 반응성이 있으며, 액상 형태로 제공됩니다. 세포막 단백질 검출에 유용하며, 신경계 연구에 적합합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 100–200 of human DRD4 (NP_0007882) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.27 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805410 |
Product Specific Information
- Immunogen sequence: AWLLSPRLCD ALMAMDVMLC TASIFNLCAI SVDRFVAVAV PLRYNRQGGS RRQLLLIGAT WLLSAAVAAP VLCGLNDVRG RDPAVCRLED RDYVVYSSVC S
- Positive Samples: Mouse brain, Rat brain
- Cellular Location: Cell membrane, Multi-pass membrane protein
Target Information
This gene encodes the D4 subtype of the dopamine receptor, a G-protein coupled receptor that inhibits adenylyl cyclase. It is a target for drugs used in the treatment of schizophrenia and Parkinson’s disease. Mutations in this gene are associated with behavioral phenotypes such as autonomic nervous system dysfunction, ADHD, and novelty seeking. The gene contains a polymorphic number (2–10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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