Thermo Fisher Scientific SGPL1 Polyclonal Antibody
SGPL1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 다클론 항체로, Western blot에 최적화되어 있습니다. 다양한 종(Bovine, Human, Mouse, Rat)에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:400
- Publications: View 2 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Human, Mouse, Rat |
| Published Species | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to sphingosine 1-phosphate lyase 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.0 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.08% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2285994 |
Product Specific Information
By Western blot, PA1-12722 detects a ~64 kDa protein representing S1P lyase 1 from MDBK cell lysate.
Target Information
Sphingosine-1-phosphate lyase cleaves phosphorylated sphingoid bases, such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. It elevates stress-induced ceramide production and apoptosis. The catalytic activity of sphingosine-1-phosphate lyase converts sphingosine-1-phosphate to phosphoethanolamine and palmitaldehyde using pyridoxal phosphate as a co-factor.
This enzyme is a type III membrane protein located in the endoplasmic reticulum and is primarily expressed in the liver and kidney. It belongs to the group II decarboxylase family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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