Thermo Fisher Scientific APPL1 Polyclonal Antibody
APPL1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, 인간, 마우스, 랫트에 반응합니다. Western blot과 ELISA에 적합하며, 고순도 친화 크로마토그래피 정제 제품입니다. 세포 증식 및 인슐린 신호 조절 연구에 활용됩니다.
- 카탈로그번호
- PA5109402
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–210 of human APPL1 (NP_036228.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.38 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2854813 |
Product Specific Information
Immunogen sequence:
MPGIDKLPIE ETLEDSPQTR SLLGVFEEDA TAISNYMNQL YQAMHRIYDA QNELSAATHL TSKLLKEYEK QRFPLGGDDE VMSSTLQQFS KVIDELSSCH AVLSTQLADA MMFPITQFKE RDLKEILTLK EVFQIASNDH DAAINRYSRL SKKRENDKVK YEVTEDVYTS RKKQHQTMMH YFCALNTLQY KKKIALLEPL LGYMQAQISF
Target Information
The protein encoded by this gene is involved in the regulation of cell proliferation and in the crosstalk between adiponectin and insulin signaling pathways. It binds multiple proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and components of the NuRD/MeCP1 complex. This protein is associated with endosomal membranes and can translocate to the nucleus upon EGF stimulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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