Thermo Fisher Scientific AQR Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:100

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 400-700 of human AQR (NP_055506.1). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:AQR,uniProtId:O60306-1,ncbiNodeId:9606,antigenRange:400-700,antigenLength:1485,antigenImageFileName:PA5-109403_AQR_O60306-1_Rabbit.svg,antigenImageFileNamePDP:PA5-109403_AQR_O60306-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.95 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2854814

Product Specific Information

Immunogen sequence: KEFLLELLVS RHERRISQIQ QLNQMPLYPT EKIIWDENIV PTEYYSGEGC LALPKLNLQF LTLHDYLLRN FNLFRLESTY EIRQDIEDSV SRMKPWQSEY GGVVFGGWAR MAQPIVAFTV VEVAKPNIGE NWPTRVRADV TINLNVRDHI KDEWEGLRKH DVCFLITVRP TKPYGTKFDR RRPFIEQVGL VYVRGCEIQG MLDDKGRVIE DGPEPRPNLR GESRTFRVFL DPNQYQQDMT NTIQNGAEDV YETFNIIMRR KPKENNFKAV LETIRNLMNT DCVVPDWLHD IILGYGDPSS A

Target Information

Involved in pre-mRNA splicing as component of the spliceosome (PubMed:11991638, PubMed:25599396, PubMed:28502770, PubMed:28076346). Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis (PubMed:16949364). Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly (PubMed:16949364). May act by helping the folding of the snoRNA sequence. Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing (PubMed:16949364). Has ATP-dependent RNA helicase activity and can unwind double-stranded RNA molecules with a 3` overhang (in vitro) (PubMed:25599396). [UniProt]

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.