Thermo Fisher Scientific RPS19 Polyclonal Antibody
RPS19 단백질을 인식하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat 시료에 반응합니다. WB와 IHC(P)에서 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 1 mg/mL 농도의 액상 제품으로, PBS와 50% glycerol buffer에 보관됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 100–145 of Human RPS19 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719292 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. Purity is greater than 95% as determined by SDS-PAGE.
Target Information
Ribosomes are organelles responsible for protein synthesis, consisting of a small 40S subunit and a large 60S subunit. These subunits include four RNA species and about 80 distinct proteins.
The RPS19 gene encodes a ribosomal protein that is part of the 40S subunit and belongs to the S19E family. It is localized in the cytoplasm.
Mutations in this gene cause Diamond-Blackfan anemia, characterized by reduced erythroid precursors. This suggests an extra-ribosomal role in erythropoietic differentiation and proliferation.
Higher expression of RPS19 has been observed in some primary colon carcinomas compared to normal colon tissue. Multiple processed pseudogenes of this gene are dispersed throughout the genome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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