Thermo Fisher Scientific ARHGDIG Polyclonal Antibody
ARHGDIG 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot 및 Immunocytochemistry에 적합하며, 인간과 생쥐 시료에 반응. 항원 친화 크로마토그래피로 정제된 고순도 제품으로 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 176–221 of Human ARHGDIG |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719289 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
The Ras superfamily of small GTP-binding proteins are critical mediators of diverse cell signaling pathways, including those leading to proliferation, cytoskeletal organization, and secretion. The counter-conversion of the active GTP-bound form of these proteins to their inactive GDP-bound form is influenced by regulatory proteins that alter intrinsic GTPase activity and GDP/GTP exchange rate. Guanine nucleotide-releasing factors (GRFs) increase the GDP dissociation rate, while GDP-dissociation inhibitors (GDIs) decrease it.
The Rho GDI subfamily includes Rho GDIα, Ly-GDI (Rho GDIβ, previously known as GDI/D4), and Rho GDIγ. These proteins interact with Ras-like GTP binding proteins such as Rho A, Rho B, Rac, and Cdc42. Ly-GDI is expressed primarily in hematopoietic cells, especially B and T lymphocyte lines.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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