Thermo Fisher Scientific Phospho-c-Jun (Ser63) Monoclonal Antibody (J.973.7)
Phospho-c-Jun (Ser63) 단백질을 검출하는 Thermo Fisher Scientific의 단클론 항체로, Western blot 및 IHC(파라핀) 실험에 적합합니다. Rabbit IgG 기반으로 고순도 친화 크로마토그래피 정제 제품이며, 인산화 c-Jun의 연구용으로 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | J.973.7 |
| Immunogen | Synthetic phosphopeptide corresponding to residues around pSer63 of human c-Jun |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 µg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | <0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_10979594 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
c-Jun is a transcription factor that recognizes and binds to the enhancer heptamer motif 5’-TGA[CG]TCA-3’.
It promotes activity of NR5A1 when phosphorylated by HIPK3, leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.
Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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