Thermo Fisher Scientific PKM2 Polyclonal Antibody
Rabbit polyclonal antibody against PKM2 protein. Suitable for IHC and other research applications. Supplied as an unconjugated liquid at 1 mg/mL concentration. Recommended storage at 4°C, shipped on wet ice. For research use only.
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Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Between amino acids 481–531 of PKM2 (UniProt ID: P14618-1, NCBI Taxonomy ID: 9606) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Application Note: For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections.
- Based on 100% sequence identity, this antibody is predicted to react with Rat, X. laevis, Chicken, Rabbit, Cat, and Orangutan.
Target Information
PKM2 (Pyruvate Kinase M2) catalyzes the conversion of phosphoenolpyruvate to pyruvate and ATP. It interacts with thyroid hormone, mediating metabolic effects of thyroid activity. PKM2 also binds to Opa protein, a bacterial outer membrane protein involved in gonococcal adherence and invasion of human cells, indicating a role in bacterial pathogenesis. Three alternatively spliced transcript variants encoding two distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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