
Thermo Fisher Scientific HO-1 Polyclonal Antibody
HO-1 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot 및 Immunoprecipitation에 사용 가능. Human에 반응하며 Mouse와 Orangutan에도 예측 반응. 항원 친화 크로마토그래피로 정제된 액상 시약으로 4°C에서 보관.
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Applications
Western Blot (WB)
- Assay-dependent
Immunoprecipitation (IP)
- 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1 and 50 of human Heme Oxygenase (decycling) 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Mouse and Orangutan
Target Information
Heme oxygenase (HO) is a microsomal enzyme that catalyzes the oxidation of heme to the antioxidant molecules biliverdin and carbon monoxide. HO consists of two homologous isozymes: inducible HO-1 and constitutively expressed HO-2.
HO-1 is induced by various stimuli such as oxidative stress, inflammatory agents, transforming growth factor beta, and heat shock. Increased HO-1 expression is considered a cellular defense mechanism against oxidative stress, as elevated HO may generate more bilirubin, an antioxidant.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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