Thermo Fisher Scientific NPTX2 Polyclonal Antibody
NPTX2 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 Immunocytochemistry에 적합합니다. 인간, 마우스, 랫트 시료에 반응하며, Affinity chromatography로 정제되었습니다. PBS/glycerol buffer에 보관되며 -20°C에서 안정적으로 저장 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human NPTX2 (Accession P47972), corresponding to amino acid residues T88–L138 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2849809 |
Product Specific Information
Antibody detects endogenous levels of total NPTX2.
Target Information
Neuronal pentraxin (NPTX) 2 is a member of the pentraxin family with high homology to NPTX1. Unlike NPTX1, NPTX2 is expressed in testes, pancreas, liver, heart, skeletal muscle, and brain. It exhibits lectin properties common to the pentraxin family, promotes neurite outgrowth, and is rapidly regulated by neuronal activity. NPTX1 and NPTX2 form heterocomplexes contributing to both activity-independent and -dependent excitatory synaptogenesis. NPTX2 is highly upregulated in Parkinsonian substantia nigra and localizes to Lewy bodies and neurites in Parkinson’s disease, suggesting involvement in PD-related pathway dysregulation.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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