Thermo Fisher Scientific PIH1D1 Polyclonal Antibody
Thermo Fisher Scientific의 PIH1D1 폴리클로날 항체는 인간, 생쥐, 랫트 시료에서 PIH1D1 단백질을 검출합니다. Western blot에 적합하며, 고순도 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며 -20°C에서 보관합니다. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human PIH1D1 (Accession Q9NWS0), corresponding to amino acid residues E84–N134 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2849816 |
Product Specific Information
Antibody detects endogenous levels of total PIH1D1.
Target Information
PIH1D1 is involved in the assembly of C/D box small nucleolar ribonucleoprotein (snoRNP) particles (PubMed:17636026). It recruits the SWI/SNF complex to the core promoter of rRNA genes and enhances pre-rRNA transcription (PubMed:22368283, PubMed:24036451). PIH1D1 mediates interaction of TELO2 with the R2TP complex, necessary for the stability of MTOR and SMG1 (PubMed:20864032), and positively regulates the assembly and activity of the mTORC1 complex (PubMed:24036451).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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