Thermo Fisher Scientific OSMR Polyclonal Antibody
Thermo Fisher Scientific의 OSMR Polyclonal Antibody는 인간, 마우스 및 비인간 영장류 시료에 반응하는 토끼 IgG 기반 항체입니다. Western blot에 적합하며, 인간 OSMR 유래 합성 펩타이드로 제작되었습니다. 액상 형태로 1 mg/mL 농도이며, PBS/glycerol buffer에 보관됩니다.
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Thermo Fisher Scientific OSMR Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:500–1:2,000
View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human OSMR (Accession Q99650), corresponding to amino acid residues C751–D801 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2849812 |
Product Specific Information
Antibody detects endogenous levels of total OSMR.
Target Information
Oncostatin M (OSM) is a member of the IL6 family of cytokines. Functional receptors for IL6 family cytokines are multisubunit complexes involving members of the hematopoietin receptor superfamily. Many IL6 cytokines utilize gp130 as a common receptor subunit.
OSM binds to the gp130 receptor subunit and, in association with the leukemia inhibitory factor receptor, induces a proliferative response in permissive cells.
OSMR acts as an alternative subunit for an OSM receptor complex (heterodimer of gp130 and OSMR) that is activated by OSM but not by LIF.
Publication Note: This RefSeq record includes a subset of the publications available for this gene. Please see the Entrez Gene record to access additional publications.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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