Thermo Fisher Scientific Caspase 6 (Cleaved Asp162) Polyclonal Antibody

Applications

Product Specifications

Product Specific Information

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1–2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Information

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family of enzymes. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic acid residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8, and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in multiple transcript variants that encode different isoforms.
[Provided by RefSeq, Oct 2015]

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.