Thermo Fisher Scientific Phospho-PPIG (Ser376) Polyclonal Antibody
Phospho-PPIG (Ser376) 폴리클로날 항체로 인간, 마우스, 랫트 반응성. Western blot, IHC, ICC/IF, ELISA 등 다양한 응용 가능. Protein A로 정제된 고순도 액상 항체로 안정적인 -20°C 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic phosphopeptide derived from human PPIG around the phosphorylation site of Ser376 [VS(p-S)GE] |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Structural Maintenance of Chromosomes (SMC) family proteins play critical roles in nuclear events requiring structural changes of chromosomes, such as mitotic chromosome organization, DNA recombination and repair, and global transcriptional repression. These chromo proteins are conserved across eukaryotes and are essential for mitotic chromosome dynamics. SMC1 and SMC3 form a heterodimeric complex required for metaphase progression and sister chromatid cohesion. Mutations in the gene can lead to Cornelia de Lange syndrome 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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