
Thermo Fisher Scientific DVL2 Monoclonal Antibody (OTI7A3), TrueMAB
인간 DVL2 단백질을 인식하는 Mouse 모노클로날 항체로 Western blot에 최적화됨. 리오필라이즈드 형태로 제공되며, PBS 버퍼에 트레할로스 포함. 재구성 후 1 mg/mL 농도로 사용 가능. 연구용으로만 사용.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7A3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–320 of human DVL2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Disheveled DVL2 is a member of the dishevelled (dsh) protein family. Vertebrate dsh proteins share approximately 40% amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kDa protein that undergoes posttranslational phosphorylation to form a 95-kDa cytoplasmic protein, which may play a role in Wnt-mediated signal transduction pathways. The mechanisms of dishevelled function in Wnt signaling are likely conserved among metazoans.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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