Thermo Fisher Scientific DVL2 Monoclonal Antibody (OTI2D11), TrueMAB
Thermo Fisher Scientific DVL2 Monoclonal Antibody (OTI2D11)은 인간 DVL2 단백질을 표적으로 하는 Mouse IgG2b 형 단일클론 항체입니다. 파라핀 포매 조직 IHC에 적합하며, 고순도 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용됩니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2D11 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–320 of human DVL2 produced in E.coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Disheveled DVL2 is a member of the dishevelled (dsh) protein family. Vertebrate dsh proteins share about 40% amino acid sequence similarity with Drosophila dsh.
This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the Wnt-mediated signal transduction pathway.
The mechanisms of dishevelled function in Wnt signaling are likely conserved among metazoans.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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