Thermo Fisher Scientific TrxR1 Polyclonal Antibody
인간 TrxR1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot과 IHC(Paraffin) 적용 가능. 항원 친화 크로마토그래피로 정제된 고품질 항체. 산화 스트레스 및 셀레늄 대사 연구에 적합. 장기 보관 시 -20°C에서 안정적 저장 가능.
- 카탈로그번호
- PA581936
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific TrxR1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human TXNRD1. Recombinant protein control fragment (Product #RP-94768) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2789097 |
Product Specific Information
Immunogen sequence:
SCEDGRALEG TLSELAAETD LPVVFVKQRK IGGHGPTLKA YQEGRLQKLL KMNGPEDLPK SYDYDLIIIG GGSGGLAAAK EAAQYGKKVM VLDFVTPTPL GTRWGLGGTC VNVGCIPKKL MHQAALLGQA LQDSRNYG
Target Information
This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenocysteine-containing genes has a common stem-loop structure, the SEC insertion sequence (SECIS), necessary for recognition of UGA as a Sec codon rather than a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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