Thermo Fisher Scientific IMPDH2 Polyclonal Antibody
인간 IMPDH2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody입니다. Western blot, IHC, ICC/IF 등 다양한 응용에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며, 안정적인 장기 보관이 가능합니다.
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Thermo Fisher Scientific IMPDH2 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human IMPDH2. Recombinant protein control fragment (Product #RP-99364) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2789099 |
Product Specific Information
Immunogen sequence:
GFITDPVVLS PKDRVRDVFE AKARHGFCGI PITDTGRMGS RLVGIISSRD IDFLKEEEHD CFLEEIMTKR EDLVVAPAGI TLKEANEILQ RSKKGKLPIV NEDDELVAII ARTDLKKNRD YPLASKD
Target Information
This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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