Thermo Fisher Scientific NPTX2 Polyclonal Antibody
Human NPTX2 단백질을 인식하는 Rabbit polyclonal 항체로, WB 및 ELISA에 최적화되어 있습니다. Recombinant fusion protein(aa 90–240)을 면역원으로 사용하며, 고순도 Affinity Chromatography 정제 제품입니다. 액상 형태로 -20°C 보관하며, 신경 관련 단백질 연구에 적합합니다.
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Thermo Fisher Scientific NPTX2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 90–240 of human NPTX2 (NP_0025141) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.43 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804818 |
Product Specific Information
- Immunogen sequence:
KLARCEGLAG GKARGAGATG KDTMGDLPRD PGHVVEQLSR SLQTLKDRLE SLEHQLRANV SNAGLPGDFR EVLQQRLGEL ERQLLRKVAE LEDEKSLLHN ETSAHRQKTE STLNALLQRV TELERGNSAF KSPDAFKVSL PLRTNYLYGK I - Positive Samples: SH-SY5Y, BxPC-3, LO2
Target Information
Neuronal pentraxin (NPTX) 2 is a member of the pentraxin family, showing high homology to NPTX1. Unlike NPTX1, NPTX2 is expressed in testes, pancreas, liver, heart, skeletal muscle, and brain. It possesses lectin properties common to pentraxins, promotes neurite outgrowth, and is regulated by neuronal activity. NPTX1 and NPTX2 form heterocomplexes contributing to excitatory synaptogenesis. NPTX2 is upregulated in Parkinsonian substantia nigra and localizes to Lewy bodies and neurites, suggesting involvement in Parkinson’s disease pathway dysregulation.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-88307_NPTX2_P47972-1_Rabbit.svg, PA5-88307_NPTX2_P47972-1_Rabbit_PDP.jpeg)
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