
Thermo Fisher Scientific Mouse IL-16 Recombinant Protein
Recombinant mouse IL-16 protein expressed in E. coli with ≥95% purity. Non-glycosylated form showing full biological activity. Suitable for cytokine signaling and T-cell activation studies. Lyophilized, endotoxin ≤0.1 EU/µg, stored at -20°C.
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Applications
- Assay-dependent
- Control (Ctrl): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Mouse |
| Expression System | E. coli |
| Amino Acid Sequence | MHDLNSSTDS AASASAASDI SVESKEATVC TVTLEKTSAG LGFSLEGGKG SLHGDKPLTI NRIFKGDRTG EMVQPGDEIL QLAGTAVQGL TRFEAWNVIK ALPDGPVTIV IRRTSLQCKQ TTASADS |
| Molecular Weight | 13.2 kDa |
| Class | Recombinant |
| Type | Protein |
| Purity | ≥95% by SDS-PAGE |
| Endotoxin Concentration | ≤0.1 EU/µg |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.1 mg/mL |
| Purification | Purified |
| Storage Buffer | 10 mM sodium phosphate, pH 7.5 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Product Specific Information
Recombinant mouse IL-16 is a non-glycosylated protein containing 127 amino acids.
It exhibits full biological activity compared to a standard.
Reconstitution Instructions:
- Reconstitute using sterile water at 0.1 mg/mL.
- Centrifuge prior to opening vial.
- Gently pipet solution down the sides of the vial.
- Do not vortex.
- Store reconstituted material at -20°C and add 0.1% BSA for additional stability.
Target Information
IL-16 encodes a pleiotropic cytokine functioning as:
- Chemoattractant
- Modulator of T-cell activation
- Inhibitor of HIV replication
The signaling process is mediated by CD4.
Proteolytic processing yields two functional proteins:
- C-terminal peptide: Cytokine function
- N-terminal product: May play a role in cell cycle control
Caspase 3 is involved in proteolytic processing.
Alternate splicing results in multiple transcript variants.
For Research Use Only.
Not for use in diagnostic procedures or resale without express authorization.
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