Thermo Fisher Scientific Human IL-2 Recombinant Protein
인간 IL-2 재조합 단백질로, E. coli에서 발현된 15.5 kDa의 고순도(≥97%) 단백질입니다. CTLL-2 세포 증식 활성 검증 완료. 면역세포 활성화 연구용으로 적합하며, 동결건조 형태로 제공됩니다. -20°C 보관.
- 카탈로그번호
- RP8608
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
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Applications
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Human |
| Expression System | E. coli |
| Amino Acid Sequence | MAPTSSSTKK TQLQLEHLLL DLQMILNGIN NYKNPKLTRM LTFKFYMPKK ATELKHLQCL EEELKPLEEV LNLAQSKNFH LRPRDLISNI NVIVLELKGS ETTFMCEYAD ETATIVEFLN RWITFCQSII STLT |
| Molecular Weight | 15.5 kDa |
| Class | Recombinant |
| Type | Protein |
| Purity | ≥97% |
| Endotoxin Concentration | ≤0.1 EU/µg |
| Activity | ED50 ≤3 ng/mL; determined by dose-dependent proliferation of CTLL-2 cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.1 mg/mL |
| Purification | Purified |
| Storage Buffer | 0.1% TFA |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Product Specific Information
Recombinant human IL-2 is a non-glycosylated protein containing 134 amino acids. It has a Serine substitution for Cysteine at position 126.
Reconstitute using sterile 10 mM HCl at 0.1 mg/mL and centrifuge prior to opening vial. Gently pipet solution down the sides of the vial. Do not vortex.
Store reconstituted material at -20°C and add 0.1% BSA for additional stability.
Target Information
Interleukin 2 (IL-2) is an immunomodulatory cytokine essential for the proliferation of activated T cells and differentiation of B cells, NK cells, monocytes, and macrophages.
IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric complex whose gamma chain is shared with IL-4 and IL-7.
Expression of the IL-2 gene in mature thymocytes is monoallelic, representing a unique regulatory mode for gene expression.
Disruption of IL-2-like genes in mice leads to ulcerative colitis-like disease, highlighting its key role in immune response regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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