Thermo Fisher Scientific V-ATPase Subunit B 2 Polyclonal Antibody
V-ATPase Subunit B2 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 ELISA에 적합합니다. 세포 내 소기관 산성화 연구에 활용되며, 고순도의 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1.0 µg/mL |
| ELISA | 0.03–0.125 µg/mL |
| Miscellaneous PubMed | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Published species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide (KLH-coupled) within residues 300–350 of human V-ATPase Subunit B2 protein (Swiss Prot: P21281) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Storage conditions | -20°C or -80°C if preferred |
| Shipping conditions | Wet ice |
Product Specific Information
The V-ATPase subunit B2 is encoded by a gene that produces a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme responsible for acidification of eukaryotic intracellular organelles. This acidification process is essential for protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation.
V-ATPase consists of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain includes three A, three B, and two G subunits, as well as C, D, E, F, and H subunits, containing the ATP catalytic site.
The protein encoded by this gene is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts.
GenScript Rabbit Anti-V-ATPase Subunit B2 Polyclonal Antibody is developed in rabbit using a synthetic peptide conjugated to KLH.
Target Information
ATP6V1B2 encodes a component of vacuolar ATPase (V-ATPase), which mediates acidification of eukaryotic intracellular organelles. This acidification is required for processes such as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation.
V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain has three A, three B, and two G subunits, as well as C, D, E, F, and H subunits, and contains the ATP catalytic site.
The encoded protein is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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