Thermo Fisher Scientific LOX Monoclonal Antibody (OTI9A11), TrueMAB
인간 LOX 단백질(aa 22-168)을 인식하는 Mouse IgG1 단클론 항체로, WB, IHC(P), ICC/IF 실험에 사용 가능. Lyophilized 형태로 제공되며, PBS 및 trehalose buffer에 보존. 세포 성장, 종양 억제, 세포 이동 등 LOX 관련 연구에 적합.
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Thermo Fisher Scientific LOX Monoclonal Antibody (OTI9A11), TrueMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:50–1:100 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI9A11 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 22–168 of human LOX produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
Lysyl oxidase (LOX) is a copper-containing amine oxidase involved in the oxidation of primary amines to reactive aldehydes.
It plays a crucial role in extracellular matrix formation and repair and is associated with biological processes such as developmental regulation, tumor suppression, cell motility, and cellular senescence.
The secreted form of LOX contributes to the invasive properties of hypoxic human cancer cells, making it an important therapeutic target for preventing and treating metastases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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