Thermo Fisher Scientific HSP90AB1 (HSP90) Monoclonal Antibody (OTI3B5), TrueMAB
HSP90 단백질을 인식하는 Mouse monoclonal antibody로 Western blot에 최적화됨. Human 시료 반응성. Lyophilized 형태로 제공되며, PBS buffer와 8% trehalose 포함. 단백질 폴딩 및 스트레스 반응 연구에 적합.
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Applications
- Western Blot (WB): 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3B5 |
| Immunogen | Full length human recombinant protein of human HSP90AA1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Heat shock proteins (HSP) are expressed in response to various biological stresses, including heat. HSP90 is a 90 kDa protein induced under stress conditions and is one of the most abundant cellular proteins under non-stress conditions.
HSP90 proteins are highly conserved molecular chaperones involved in:
- Signal transduction
- Protein folding and degradation
- Morphologic evolution
They associate with cochaperones and assist in folding newly synthesized proteins or refolding denatured proteins after stress.
HSP90 interacts with intracellular proteins such as steroid receptors, actin, tubulin, aryl hydrocarbon receptor, and several kinases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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