Thermo Fisher Scientific MEK1 Polyclonal Antibody
MEK1 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC 및 IHC(P) 실험에 적합합니다. Human을 포함한 다양한 종에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 4°C에서 보관하며 연구용으로만 사용됩니다.
- 카탈로그번호
- IHC00619x (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific MEK1 Polyclonal Antibody
Applications
Immunohistochemistry (IHC)
- Tested Dilution: 1:100–1:500
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 343 and 393 of human MAPK/ERK kinase 1 (Dual specificity mitogen-activated protein kinase kinase 1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with X. laevis, X. tropicalis, Chicken, Turkey, Bovine, Dog, Horse, Rabbit, Pig, Panda, Monkey, Gorilla, and Chimpanzee
Target Information
MAP2K1 (MEK1) kinase is a dual-specificity protein kinase functioning in mitogen-activated protein kinase (MAPK) cascades, regulating cell growth and differentiation.
It is activated by various growth factors, cytokines, membrane depolarization, and calcium influx.
Phosphorylation of serine 218 and 222 residues by Raf1 activates MEK1.
MEK1 plays roles in stress response signaling, apoptosis, and cytokine-induced proliferation.
Mutations in the MAP2K1 gene can lead to cardiofaciocutaneous syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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