Thermo Fisher Scientific MEK2 Polyclonal Antibody
MEK2 단백질을 표적으로 하는 Thermo Fisher Scientific의 rabbit polyclonal antibody. IHC 및 IHC (Paraffin) 실험에 적합하며, 인간 및 여러 종에 반응 예측됨. 액상 형태로 제공되며 항원 친화 크로마토그래피로 정제됨. 연구용으로만 사용 가능.
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Thermo Fisher Scientific MEK2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (IHC) | 1:100–1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1 and 50 of human MAPK/ERK kinase 2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Mouse, Dog, Guinea pig_10141, Pig, Panda, Monkey, Gorilla, Northern white-cheeked gibbon, Gray short-tailed opossum, and Ferret
Target Information
MAP2K2 (MEK2) is a dual specificity serine/threonine kinase involved in mitogen growth factor signal transduction.
MEK2 (MAPKK2) activates ERK1/2 and MAPK enzymes by phosphorylating residues in the TEY motif within the activation loop.
MEK1 and MEK2 are activated by dual phosphorylation on serine 218 and 222.
Threonine 292 of MEK1 is phosphorylated by ERK2, providing a negative feedback mechanism that suppresses MEK1 activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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