Thermo Fisher Scientific SIGLEC5 Polyclonal Antibody
SIGLEC5 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western Blot 및 ELISA에 적합. 인간 시료 반응성, 고순도 친화 크로마토그래피 정제. 액상 형태로 안정적이며 -20°C에서 보관. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Concentration: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 17–434 of human SIGLEC5 (NP_0038211) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 4.51 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2855781 |
Product Specific Information
Immunogen sequence:
EKPVYELQVQ KSVTVQEGLC VLVPCSFSYP WRSWYSSPPL YVYWFRDGEI PYYAEVVATN NPDRRVKPET QGRFRLLGDV QKKNCSLSIG DARMEDTGSY FFRVERGRDV KYSYQQNKLN LEVTALIEKP DIHFLEPLES GRPTRLSCSL PGSCEAGPPL TFSWTGNALS PLDPETTRSS ELTLTPRPED HGTNLTCQMK RQGAQVTTER TVQLNVSYAP QTITIFRNGI ALEILQNTSY LPVLEGQALR LLCDAPSNPP AHLSWFQGSP ALNATPISNT GILELRRVRS AEEGGFTCRA QHPLGFLQIF LNLSVYSLPQ LLGPSCSWEA EGLHCRCSFR ARPAPSLCWR LEEKPLEGNS SQGSFKVNSS SAGPWANSSL ILHGGLSSDL KVSCKAWNIY GSQSGSVLLL QGRSNLGT
Target Information
SIGLEC5 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells.
It binds equally to α2,3-linked and α2,6-linked sialic acid.
The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
This molecule is expressed by monocytic/myeloid lineage cells, found at high levels in peripheral blood leukocytes, spleen, and bone marrow, and at lower levels in lymph node, lung, appendix, placenta, pancreas, and thymus.
It is expressed by monocytes and neutrophils but absent from leukemic cell lines representing early stages of myelomonocytic differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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