Thermo Fisher Scientific ALKBH7 Polyclonal Antibody
Thermo Fisher Scientific의 ALKBH7 Polyclonal Antibody는 인간, 마우스, 랫트에 반응하는 토끼 유래 IgG 항체로, Western blot과 ELISA에 사용됩니다. 재조합 단백질(aa 1-221)을 면역원으로 하며, 액상 형태로 제공되고 -20°C에서 보관합니다.
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Thermo Fisher Scientific ALKBH7 Polyclonal Antibody
Applications and Tested Dilutions
- Western Blot (WB): 1:200–1:2,000
- ELISA: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 1–221 of human ALKBH7 (NP_115682.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.96 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS (pH 7.3) with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2855783 |
Product Specific Information
Immunogen sequence:
MAGTGLLALR TLPGPSWVRG SGPSVLSRLQ DAAVVRPGFL STAEEETLSR ELEPELRRRR YEYDHWDAAI HGFRETEKSR WSEASRAILQ RVQAAAFGPG QTLLSSVHVL DLEARGYIKP HVDSIKFCGA TIAGLSLLSP SVMRLVHTQE PGEWLELLLE PGSLYILRGS ARYDFSHEIL RDEESFFGER RIPRGRRISV ICRSLPEGMG PGESGQPPPA C
Target Information
ALKBH7 (alkB, alkylation repair homolog 7), also known as SPATA11, is a 221 amino acid protein belonging to the alkB family.
ALKBH7 is one of many homologs of the Escherichia coli protein AlkB, which protects DNA and RNA against damage from environmental methylating compounds by directly reversing 1-methyladenine (1-meA) and 3-methylcytosine (3-meC) alkylation lesions.
The enzyme acts through oxidative demethylation using ferrous iron and alpha-ketoglutarate as cofactors, 2-oxoglutarate as co-substrate, and molecular oxygen as the oxidizing agent.
The ALKBH7 gene is located on human chromosome 19, known for its high gene density.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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