Thermo Fisher Scientific Phospho-p130Cas (Tyr410) Recombinant Rabbit Monoclonal Antibody (23GB3870)
Phospho-p130Cas (Tyr410)을 특이적으로 인식하는 재조합 토끼 단클론 항체. Western blot과 유세포분석에 적합. 인간, 마우스, 랫트 반응성. 액상 형태로 공급되며 -20°C에서 보관. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:5,000
Flow Cytometry (Flow)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 23GB3870 |
| Immunogen | A synthetic peptide of human Phospho-BCAR1 (Tyr410) (403–417 AA) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
The p130Cas (Cas for Crk-associated substrate) is a common cellular target of phosphorylation signaling via v-Crk and v-Src oncoproteins.
It has a unique structure containing a Src homology (SH)-3 domain followed by multiple YXXP motifs and a proline-rich region.
p130Cas is implicated in various biological processes, including:
- Cell adhesion and migration
- Growth factor stimulation
- Cytokine receptor engagement
- Bacterial infection
Physiological functions include cardiovascular development, actin filament assembly, and Src-induced cell transformation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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