Thermo Fisher Scientific ATG16L1 Recombinant Rabbit Monoclonal Antibody (23GB665)
ATG16L1 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot, ICC/IF, Flow cytometry에 적합합니다. 인간, 마우스, 랫트 반응성이 있으며, 고순도의 액상 형태로 제공됩니다. 자가포식 연구 및 ATG16L1 단백질 발현 분석에 유용합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunocytochemistry (ICC/IF) | 1:1,000 |
| Flow Cytometry (Flow) | 1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 23GB665 |
| Immunogen | Synthetic peptide of human ATG16L1 (1–150 AA) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
Autophagy related protein 16L (ATG16L1) is encoded by the ATG16L gene located on chromosome 2 in humans. It is also known as WD30 or IBD10 (Inflammatory Bowel Disease 10).
ATG12 and ATG5 conjugate and oligomerize with ATG16L to form an 800 kDa Atg16L complex, which facilitates LC3 lipidation to phosphatidylethanolamine (PE). This ubiquitin-like conjugation system serves as a key marker for autophagy.
The ATG16L complex, along with ATG18 and ATG21, prevents premature cleavage of ATG8-PE by Atg4 until autophagosome completion.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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