Thermo Fisher Scientific HPS3 Polyclonal Antibody

Applications and Tested Dilution

• Western Blot (WB): 1–3 µg/mL

Product Specifications

Product Specific Information

• Recommended positive controls: The peptide used to generate this antibody is available for purchase (GTX19047-PEP).
• Store product as a concentrated solution.
• Centrifuge briefly prior to opening the vial.

Target Information

This gene encodes a protein containing a potential clathrin-binding motif, consensus dileucine signals, and tyrosine-based sorting signals for targeting to vesicles of lysosomal lineage.
The encoded protein may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes.
Mutations in this gene are associated with Hermansky-Pudlak syndrome type 3. Alternate splice variants exist, but their full-length sequence has not been determined.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.